Abstract Background We aimed to investigate the effect and potential mechanism of enhancing Neuregulin1 (NRG1)/v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4 (ErbB4) expression on the differentiation of induced pluripotent stem cells (iPSCs) into cardiomyocytes.Methods We utilized CRISPR-CAS9 technology to knock in ErbB4 and obtain
The Chinese tourism industry has been developing rapidly for the past several years, and the number of people traveling has been increasing year by year.However, many problems still beset current tourism management.Lack of effective management has caused numerous problems, such as tourists stranded during tourist season and the declining service qu
Abstract Background In China, a rapid expansion of Hand, foot, and mouth disease (HFMD) outbreaks has occurred since 2004 and HFMD has become an important issue for China.However, people are still only concerned with human enterovirus 71(HEV-71) and coxsackie virus A16 (CV-A16).Much of what is known about the other enterovirus infections relies on
Abstract soderhamn ottoman cover Rich freshwater biodiversity is threatened by increasing deforestation and disorderly urbanization throughout the Brazilian Amazon, especially in streams and creeks, leading to loss of aquatic habitats.Biological information combined with habitat and water quality are effective tools for rapid assessment.The impact
Abstract Air pollution is a significant and pressing environmental and public health concern in urban areas, primarily driven by road transport.By gaining a deeper understanding of how traffic dynamics influence air pollution, policymakers and experts can design targeted interventions to tackle these critical issues.In order to analyse this relatio